·Comment·
Comment
on “Role of corneal collagen fibrils in corneal disorders and related
pathological conditions”
Khosrow Jadidi1, Hossein Aghamollaei2
1Vision
Health Research Center, Semnan University of Medical Sciences, Semnan
3519899951, Iran
2Chemical
Injuries Research Center, Systems biology and Poisonings Instituate,
Baqiyatallah University of Medical Sciences, Tehran 411435453685, Iran
Correspondence
to: Hossein
Aghamollaei. Chemical Injuries Research Center, Systems biology and Poisonings
Instituate, Baqiyatallah University of Medical Sciences, Mollasadra St., Tehran
411435453685, Iran. aghmolaei22@gmail.com
Received:
DOI:10.18240/ijo.2019.06.30
Citation: Jadidi
K, Aghamollaei H. Comment on “Role of corneal collagen fibrils in
corneal disorders and related pathological conditions”. Int J Ophthalmol
2019;12(6):1056
Dear Editor,
We read with
interest the review article “Role of corneal collagen fibrils in corneal
disorders and related pathological conditions” by Zhou et al[1]. We would like to point out the mistake that is made in
the parts of the article.
In the
“CORNEAL COLLAGEN DEGRADATION” section, the authors reviewed the process and
factors that influence the corneal collagen and extra cellular matrix. In this
section, keratinocyte was introduced as a source of myofibroblast which have a
critical role in the corneal stroma wound healing process. Production of metrix
metalloproteinase 1 by keratinocyte is indicated and emphasized that this
process is mediated by interleukin-1 (IL-1), plasminogen, and urinary
plasminogen activator (uPA). They referred this statements to Sougioca et al[2] and Zhou and Petroll[3].
With regard to these studies and several others it is noticeable that the
corneal stromal cells are “keratocytes” not “keratinocytes”. The role of
keratocyte in stromal function and corneal repair is approved and reviewed in
West-Mays and Dwivedi[4] and Petroll and
Miron-Mendoza[5].
Although
keratinocytes are present in other part of ocular surface such as conjunctiva
and limbus[6-7], but presence and
function of this type of cells in corneal stroma is not reported. So,
“keratinocyte” in mentioned section as well as “CORNEAL COLLAGEN CONTRACTION”
section should be changed to “keratocyte”.
ACKNOWLEDGEMENTS
Conflicts of
Interest: Jadidi K, None; Aghamollaei H, None.
REFERENCES