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Citation: De Bernardo M, Abbinante G, Cembalo G, Rosa N. Comment on “Two-stage procedure in the management of selected cases of keratoconus: clear lens extraction with aspherical IOL implantation followed by WFG-PRK”. Int J Ophthalmol 2019;12(8):1369-1370. DOI:10.18240/ijo.2019.08.24


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Comment·

 

Comment on “Two-stage procedure in the management of selected cases of keratoconus: clear lens extraction with aspherical IOL implantation followed by WFG-PRK”

 

Maddalena De Bernardo, Giulia Abbinante, Giovanni Cembalo, Nicola Rosa

 

Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, Baronissi 84081, SA, Italy

Correspondence to: Maddalena De Bernardo. Department of Medicine, Surgery and Dentistry “Scuola Medica Salernitana”, University of Salerno, Via S. Allende, Baronissi 84081, Salerno, Italy. mdebernardo@unisa.it

Received: 2018-12-28        Accepted: 2019-06-11

 

DOI:10.18240/ijo.2019.08.24

 

Citation: De Bernardo M, Abbinante G, Cembalo G, Rosa N. Comment on “Two-stage procedure in the management of selected cases of keratoconus: clear lens extraction with aspherical IOL implantation followed by WFG-PRK”. Int J Ophthalmol 2019;12(8):1369-1370

 

Dear Editor,

We read with great interest the article by Abou Samra et al[1] about the management of selected keratoconus cases.

We would like to congratulate the authors for the originality of this study, but in our opinion there are some points that need to be clarified.

The authors included in this study 13 eyes of 11 patients. This number seems to be too small, to make a definite conclusion. Moreover from this number it is clear that in some patients both eyes have been evaluated while, in the others, only one eye has been evaluated, introducing in this way a bias in the study.

Another problem is related to the way the astigmatic correction has been estimated. According to the published data, it seems that astigmatic correction has been assessed without taking into account the vector analysis, which in these cases is mandatory, because it is necessary to analyze both the astigmatic power and the axis changes. In fact, a shift of the astigmatic axis correction could influence both astigmatic and spherical changes, and the only way to detect such influence is the vector analysis[2-3].

Another issue that we would like to comment is the choice to perform a wave front-guided photorefractive keratotomy (WFG-PRK) without cross linking. In our opinion this could be dangerous, because keratoconus is an evolutionary disease over a period of months, so the 6mo follow-up would not be sufficient to rule out a possible slatentization after surface refractive surgery.

To support their choice, the authors cited some papers previously published, but the reported papers seem to be quite different. In fact Sachdev et al[4] analyzed healthy patients who underwent photorefractive keratotomy (PRK) versus patients with fruste keratoconus, who underwent corneal collagen cross-linking (CXL) and PRK, Xie et al[5] analyzed patients with keratoconus who underwent PRK after a previous epikeratophakia, and lastly Khakshoor et al[6] assessed patients with naturally stable keratoconus or after crosslinking, making in all these cases the comparison with the patients described in the paper by Abou Samra et al[1] meaningless.

Lastly, as the authors utilized Pentacam to detect the keratoconus progression, we would like to suggest to utilize the corneal volume instead of the minimum corneal thickness to detect such a progression[7-10].


ACKNOWLEDGEMENTS

Conflicts of Interest: De Bernardo M, None; Abbinante G, None; Cembalo G, None; Rosa N, None.


REFERENCES

1 Abou Samra W, Mokbel T, Elwan M, Saleh S, Elwehidy A, Iqbal M, Ellayeh A. Two-stage procedure in the management of selected cases of keratoconus: clear lens extraction with aspherical IOL implantation followed by WFG-PRK. almol 2018;11(11):1761-1767.
https://doi.org/10.18240/ijo.2018.11.05

2 De Bernardo M, Cornetta P, Rosa N. Safety and efficacy of sequential intracorneal ring segment implantation and cross-linking in pediatric keratoconus. Am J Ophthalmol 2017;181:182-183.
https://doi.org/10.1016/j.ajo.2017.06.039
PMid:28778569

 

3 Rosa N, De Bernardo M, Romano MR, Scarfato G, Verdoliva F, Mastropasqua R, Lanza M. Analysis of photoastigmatic keratectomy with the cross-cylinder ablation. Indian J Ophthalmol 2012;60(4):283-287.
https://doi.org/10.4103/0301-4738.98707
PMid:22824597 PMCid:PMC3442463

 

4 Sachdev GS, Ramamurthy S, Dandapani R. Comparative analysis of safety and efficacy of photorefractive keratectomy versus photorefractive keratectomy combined with crosslinking. Clin Ophthalmol 2018;12:783-790.
https://doi.org/10.2147/OPTH.S156500
PMid:29750010 PMCid:PMC5933339

 

5 Xie L, Gao H, Shi W. Long-term outcomes of photorefractive keratectomy in eyes with previous epikeratophakia for keratoconus. Cornea 2007;26(10):1200-1204.
https://doi.org/10.1097/ICO.0b013e31815654a5
PMid:18043176

 

6 Khakshoor H, Razavi F, Eslampour A, Omdtabrizi A. Photorefractive keratectomy in mild to moderate keratoconus: outcomes in over 40-year-old patients. Indian J Ophthalmol 2015; 63(2):157-161.
https://doi.org/10.4103/0301-4738.154400
PMid:25827548 PMCid:PMC4399126

 

7 De Bernardo M, Rosa N. Central corneal thickness after cross-linking using high-definition optical coherence tomography, ultrasound, and dual scheimpflug tomography: a comparative study over one year. Am J Ophthalmol 2017;176:254.
https://doi.org/10.1016/j.ajo.2017.01.007
PMid:28159112

 

8 De Bernardo M, Borrelli M, Mariniello M, Lanza M, Rosa N. Pentacam vs SP3000P specular microscopy in measuring corneal thickness. Cont Lens Anterior Eye 2015;38(1):21-27.
https://doi.org/10.1016/j.clae.2014.08.006
PMid:25240777

 

9 De Bernardo M, Rosa N. Re: Hersh et al.: US multicenter clinical trial of corneal collagen crosslinking for treatment of corneal ectasia after refractive surgery (Ophthalmology. 2017;124: 1475-1484). Ophthalmology 2018;125(6):e39.
https://doi.org/10.1016/j.ophtha.2018.01.037
PMid:29784099

 

10 De Bernardo M, Rosa N. Repeatability and agreement of orbscan II, pentacam HR, and Galilei tomography systems in corneas with keratoconus. Am J Ophthalmol 2018;186:166.
https://doi.org/10.1016/j.ajo.2017.10.036
PMid:29221823