·AIM:To analyse and explore the incidence,clinical characteristics and correlated factors of steroids induced high intraocular pressure(IOP)after excimer laser cornea refractive surgery,then make a help for clinic.·METHODS:Retrospective study of high IOP of 1580 patients(3160 eyes)after laser in situ keratomileusis(LASIK)or laser subepithelial keratomileusis(LASEK)from 2005 to 2009 was performed in our hospital.·RESULTS:Sixty-eight eyes in 38 cases of steroids induced high IOP were recognized.The incidence rate was 2.2%.There were 20 male cases and 18 female cases.The age of the patients ranged from 18-33 years old.The spherical equivalent refraction were-4.00--12.00D.It occurred from 14-30 days after excimer laser cornea refractive surgery.There were 16 cases(30 eyes)and 22 cases 38 eyes occurred steroids induced high IOP after LASIK and LASEK,respectively.Fluorometholone or prednisolone acetate eye drops were topically used on 68 eyes.The time with eyedrops was from 20 days to 90 days.The eyesight of 38 patients 68 eyes decreased with different degree and intraocular pressure increased,and some patients had corneal epithelium edema.The eyesight of all patients recovered to normal and the symptoms of them disappeared after stoping the steroids,and giving topical or systemic antiglaucoma agents according to patients’ intraocular pressure.·CONCLUSION:There were special features in steroids induced high IOP after excimer laser cornea refractive surgery.The clinician should pay more attention to these cases to avoid misdiagnosis.·