Posterior capsule opacification(PCO) is a subsequent complication after the implantation of the artificial lens from the extracapsular cataract extraction. The lens epithelial cells after the operation play the key factors. The most important way to treat PCO is to avoid the growth and transposition of the lens epithelial cells,which is similar to the treatment of the tumor. So, the difficulty in the study is how to choose the best method of drug administration which can keep the effective concentration of the drug and reduce its side effect. This thesis summarizes the routes of drug administration in the treatment of PCO.