AIM:To evaluate the safety,efficiency and repeatability of using the Knife 90 of Moria-M2 to make corneal flap in LASIK.METHODS:Five hundred cases 1000 eyes were performed by Knife 90 and 510 cases 1010 eyes were performed by Knife 130,and the shape,thickness,diameter,pedice length and complication of the corneal flap were observed and compared by two different knives.RESULTS:The thickness of corneal flap with 90 heads was 90-120μm and the average was 105.5±15.5μ m,but the thickness of corneal flap with 130 heads was130-160μm and the average was 145±15μm.There was significantly statistical difference.There was no significantly statistical difference in corneal flap diameter,corneal flap pedicle length,curvature,shape and other complications with two different heads.CONCLUSION:It is very safe,efficient and repeatable to use the Knife 90 of Moria-M2 to make corneal flap,the surface of corneal flap are smooth and clean,and the Knife 90 is easy to operate and maintain.