AIM:To evaluate the performance of dynamic contour tonometer(DCT)before and after LASEK surgery by applying mitomycin C.METHODS:Three hundred eyes of 150 myopic patients admitted in our hospital were included in this study.The left and right of eyes of 150 patients was randomly divided into two groups,0.2g/L MMC sponge was put onto the cornea ablation area in 2 minutes during the operation in 150 eyes of MMC group;BSS sponge was put onto the cornea ablation area in 2 minutes during the operation in 150 eyes of the control group.The IOP was measured with DCT before operation and 1 week and 4,12 weeks after operation.RESULTS:The IOP in MMC group and control group was 17.17±2.35mmHg,18.12±2.41mmHg before opera-tion respectively.The IOP in MMC group and control group was 17.09±2.72mmHg,17.24±2.39mmHg,17.12±2.67mmHg,17.52±2.47mmHg,18.01±2.69mmHg,17.66±2.54mmHg 1 week and 4,12 weeks after the operation respectively.There was no difference of DCT in the control group and MMC group at various time point after the operation respectively.CONCLUSION:DCT may be suitable for monitoring IOP in eyes that have had corneal refractive surgery.The application of MMC in LASEK has no effect on the IOP.