·AIM:To elucidate the relationship between human the-laziasis and canine infection with Thelazia callipaeda in Wuhe county.·METHODS:The were insect vector of Thelazia callipaeda and epidemiological information on the thelaziasis before and after dog-raising control investigated.·RESULTS:The fruit fly Amiota okadai was confirmed to be the transmission vector of this disease in 1989;seventeen human cases(all are infants and young children)were reported during 1985-2008 in this county and the prevalence of canine Thelazia callipaeda infection was found to be 86.9% during this period.31 dogs were examined in September 1998 and no animals were found to be infected with this nematode.·CONCLUSION:Infective resources are controled due to the dog-raising control and human thelaziasis are eradicated in this rural area.·