·AIM:To investigate the clinical effect of epipolis laser in situ keratomileusis(Epi-LASIK)without flap by mechanical method for correction of high myopia.·METHODS:Totally 86 patients 169 eyes with high myopia were performed Epi-LASIK without flap.Patients were followed up for 6 months.Postoperative irritation,corneal epithelial healing time,visual acuity,refraction,degree of corneal haze were observed.·RESULTS:All patients presented only with a mild to moderate foreign body sensation,photophobia,tearing.Corneal epithelial healing time was 3-4 days.After 6 months,postoperative spherical equivalent in all patients were within 1.00D,and no decline in best-corrected visual acuity,Best-corrected visual acuity improved 1 line or more in 23 eyes(13.6%).Corneal haze grade 0 in 142 eyes(84.0%),corneal haze 0.5 in 27 eyes(16.0%)1 month after surgery;after 3 months,corneal haze grade 3 in 2 cases 4 eyes with unknown causes;6 months after surgery,all corneal haze present 0.·CONCLUSION:Epi-LASIK flap for high myopia is a safe and effective method,with good predictability and stability.The further study should continue on the unexplained postoperative haze of individual patients.·