AIM:To investigate the effective treatment methods of neovascular glaucoma.METHODS:Sixty-eight patients 78 eyes with neovascular glaucoma were randomly divided into two groups.Normal group was performed ciliary body cryotheraby,experimental control group were treated with ciliary body cryotheraby combined with trabeculectomy and 5-FU.Two groups of patients after operation both dropped eye drops and accepted preventive anti-infective therapy for one week.Postoperative follow-up time was from 1 month to 2 years.RESULTS:The success rate of the control group(42%).Experimental control group success rate(72%).There was significant difference between two groups(P<0.05).CONCLUSION:Ciliary body cryotheraby combined with trabeculectomy and 5-FU are effective treatment of neovascular glaucoma.