AIM:To clarify characteristic of clinic and fundus fluorescein angiography(FFA)in parafoveal telangiectasis.METHODS:The clinical data of 22 parafoveal telangiectasis patients 22 eyes diagnosed with FFA in our out-patient clinic from 2004 to 2008 were analyzed retrospectively.RESULTS:The mean age was 53.03±12.43 years old,10 patients were male,others were female.The mean vision was 0.32±0.28.Two patients were diabetic.The diseased region located in bitamporal parafovea.The fundus displayed retinal local edema in the diseased region,surrounding with yellow-white hard exudates,few bleeding,the extent of disease was from 1PD×0.5PD to 4PD×3PD.FFA showed nodule dilated capillary at parafovea in early stage,the macular circle was destroyed.The part displayed right angled venules.The late stage showed suffusion hyperfluorescence.CONCLUSION:The parafoveal telangiectasis often happens in fifty years old people,and no significant difference in gender,all cases are unilateral,the extent of disease is more than 1PD,the diseased region locates in bitamporal parafovea.Abnormal blood sugar maybe influence development of parafoveal telangiectasis.