AIM:To observe the curative effect of augentropfen stulln mono on astigmatism in early childhood.METHODS:In a prospective,randomized and controlled method,by atropine eye ointment cycloplegic refraction,80 cases in 3-7 years old with more than 1D astigmatism were randomly divided into two groups.40 cases were applied augentropfen stulln mono 3-4 times per day for 3 months,and the other 40 cases were taken as control group.After 3 months,both groups were taken atropine mydriasis optometry again,the refractive status were compared before and after using the drops,and adverse drug reactions were observed,the number of times per minute blink were counted.RESULTS:After 3 months treatment,astigmatism was significantly reduced compared with before treatment(P<0.05).A decrease in the number of blinks per minute was also observed.Drug group did not have any adverse reactions.CONCLUSION:The treatment of astigmatism with augentropfen stulln mono in early childhood is safe,convenient and effective.