·AIM:To compare overall visual acuity and the rate of spectacle independence after implantation of ReSTOR multifocal intraocular lens(IOL)and Natural single-focal IOL in patients with age-related cataract.METHODS:A total of 27 patients with age-related cataract were divided into two groups at random.One group of 12 patients(15 eyes)received ReSTOR multifocal IOL,another group of 15 patients(18 eyes)received Natural single-focal IOL.3 months after surgery,we observed patient’s best-corrected distance visual acuity(BCDVA),distance-corrected near visual acuity(DCNVA),independence on spectacles and the distance-corrected visual acuity in distance of 40cm,63cm and 100cm.RESULTS:BCDVA in the multifocal group were not statistically different from the single-focal group.DCNVA,independence on spectacles and the distance-corrected visual acuity in distance of 40cm,63cm and 100cm were statistically better in the multifocal group compared with the single-focal group(P<0.05).CONCLUSION:The ReSTOR multifocal IOL may obtain excellent overall visual acuity.