·AIM:To compare clinical significance of the phoroptor and compound tropicamide eye drops in optometry of juvenile myopes aged 12 to 16.METHODS:From January to September in 2009,100 juvenile myopes(200 eyes)aged 12-16(mean age 14.5,male 80 eyes,female 120 eyes)were included in this study.Their diopter was 0.50-4.50DS,astigmatism was 0.50-2.00DC and examinations were performed to exclude ophthalmopathy.The results of the phoroptor and compound tropicamide eye drops in optometry were compared.RESULTS:The mean diopter for phoroptor was-1.68±0.80D.After compound tropicamide eye drops cycloplegic refraction the mean diopter was-1.54±0.80D.The results of optometry for phoroptor was higher than that of compound tropicamide eye drops mydriasis,the difference was significant(P<0.05).CONCLUSION:For 12-16 years old newly diagnosed juvenile myopes,the compound tropicamide eye drops should be widely used in clinical application,as the optometry result of the compound tropicamide eye drops is more reliable than phoroptor.