AIM:To compare the higher-order aberrations between implantations of AcrySof and AcrySof ReStor multifocal aspherical intraocular lens(IOL)with various pupil diameters.METHODS:Fifty-four patients(62 eyes)with bilateral senile cataracts were retrospectively selected.Patients were operated with phacoemulsification and IOL implantation.They were divided into two groups based on the IOL implantation of AcrySof IQ and AcrySof ReStor.Wave front aberration:spherical aberration(C12)and the root mean square of the total higher-order aberration(RMSh)were observed 3 months after surgery.RESULTS:The larger the pupil was,the higher the C12 and RMSh were in the eyes(P<0.01).There were no statistical differences in C12 or RMSh between two groups at 5,6 or 7mm pupil diameters(P>0.05).CONCLUSION:There are no differences between AcrySof IQ group and AcrySof ReStor group at 5,6 or 7mm pupil diameters.