AIM:To investigate the methods and effects of Amniotic membrane transplantation for treatment of symblepharon by severe eye burns. METHODS:Chemical burns or thermal burns could lead to conjunctival sac stenosis and symblepharon,which caused pseudo-deformation of eye surface, tear dynamics change and eyeball movement disorders.This study uesd amniotic membrane transplantation for reconstruction the ocular surface shape and conjunctival sac. RESULTS:Twenty-three patients were followed up for 4 to 27 months,corneal pseudopterygium recurred for 2 patients, but the conjunctival sacs were improved, and conjunctival sac were reduced in 4 mild patients and 2 moderate; the other patients could better reconstruct ocular surface. CONCLUSION:Amniotic membrane transplantation has a better effect in the treatment for ocular surface shape of symblepharon because of severe eye burns.