AIM:To evaluate the clinical results of laser subepithelial keratomileusis (LASEK) in the correction of high and super-high myopia.METHODS:LASEK was performed on 271 cases(493 eyes) with myopia who were divided into a high myopia group(6.00-10.00D) and a super-high myopia group(≥10.00D) on the basis of the preoperative spherical equivalent refraction.The high myopia group was 311 eyes and the other group was 182 eyes.The follow-up time was 1 year.The postoperative uncorrected visual acuity(UCVA),haze and other complications were compared between the two groups.RESULTS:The postoperative UCVA raised in all eyes.At the end of 1 year,there were 255 eyes (82.0%) in high myopia group and 110 eyes (60.4%) in the other one of which the postoperative UCVA was better than the preoperative best-corrected visual acuity (BCVA).The differences were statistically significant between the two groups (P<0.01).The all hazes were within 2 grade.There weren’t apparent cornea irritation and severe complications.CONCLUSION:LASEK was a safe,effective method for high myopia,but not effective for super-high myopia.