To study the clinical effect of a new type of probe to treat congenital nasolacrimal duct obstruction(NLDO) according to the characteristics of the infant, such as age, head not being easily fixed, tissue tenderness and not suitable for manipulation repeatedly. METHODS：All 2568 infants(2771 eyes) who have congenital NLDO received probing of lacrimal passages with the new type probing needle and were observed in the clinic service. RESULTS: All eyes could be probed successfully, especially 2722 eyes (98.23%) could be probed successfully one time and 49 eyes (1.77%) were two times. There were not any severe complications but gentle palpebral edema. CONCLUSION: New onetime probing needle which are reasonable designed are convenient, safe and practical to use. They have no hurt to lacrimal passage. At the same time, they can be packed and sterilized independently to avoid cross contamination. This new type, low price needle which is particularly suitable for infant has good therapeutic effect and deserves to be spread to use.