To investigate the effect of trabeculectomy combined with vitreous aspiration in treating malignant glaucoma. METHODS:Nineteen patients (20 eyes) with shallowing of the anterior chamber and high intraocular pressure following trabeculectomy were treated with viscoelastics injected to the anterior chamber combined with vitreous aspiration. RESULTS:The intraocular pressure of 19 patients ranged from 5 to 22.5 mmHg, the average was 10.4 mmHg .The visual acuity of 5 patients (6 eyes) increased, and the visual acuity of 9 patients(9 eyes) declined. Vitreous hemorrhage occurred in 3 patients (3 eyes). CONCLUSION:The pathogenesis of malignant glaucoma includes forward displacement of the ciliary body and lens. Trabeculectomy combined with vitreous aspiration can prevent malignant glaucoma effectively.