AIM:To research the correlation between the physiological blind spot visual field variation and optic disc parameters detected by microperimetry-1(MP-1), short-wavelength automated perimtry/blue-on-yellow perimetry(SWAP/B-YP), standard white-on-white perimetry(W-WP)in the modern clinical comprehensive detection of glaucoma patients.

METHODS:The optic area visual field detection in 39 cases of 78 normal physical examinees(all soldiers), 59 cases 118 eyes with early stage of glaucoma, 25 cases 50 eyes with middle stage of glaucoma was detected using HUMPHREY Ⅱ-750 automated full field perimetry, SWAP/B-YP, MP-1, and precisely positioned by 45° non-mydriatic fundus camera and superimposed. The data obtained by the three perimeters were analyzed. Key indicators included cup/disc(C/D)ratio and mean deviation(MD).

RESULTS: There was obvious difference in the MP-1 and SWAP/B-YP. Compared with the normal physical examinees, C/D, MD enlarged in patients with early stage of glaucoma, and physiological blind spot was slightly enlarged, and there were obvious variations in blind spot, MS, MD observed in patients with middle stage glaucoma by the three perimeters. When glaucoma was detected by MP-1 combined SWAP/B-YP, with the guidance of Logistic regression analysis, the specificity, sensitivity, accuracy rate of MD was 92.0%,95.0%,93.9%, respectively, and after the comprehensive analysis of C/D, the rate could surpass 99%.

CONCLUSION: The sensitivity of MP-1 and SWAP/B-Y was higher in detection of early stage of glaucoma than standard W-WP, and they had good correlation, but for the advanced glaucoma, W-WP was fast, accurate, and time-saving, The above three perimeters can fully reflect that 45° non-mydriatic fundus camera combined with the visual field function comprehensive analysis, which combines morphology and fuctionial study to get the precise and quantitative materials of visual function, can improve the clinical diagnosis effect of glaucoma.