AIM: To observe and analyze the clinical effect of minimal occlusion + Haidinger brush + flicker red light + distance visual function training of red E standard logarithm visual acuity chart in treating children with myopic amblyopia.

METHODS: Totally 97 children(186 eyes)with myopic amblyopia were treated, 47 children(89 eyes)in group A aged 4-12(5.79±1.98)years old were treated by covering + flicker red light + near visual function training and 50 children(97 eyes)in group B aged 3-10(5.92±1.72)years old were treated by minimal covering + Haidinger brush + flicker red light + distance visual function training of red E standard logarithm visual acuity chart. The patients with mild myopia, moderate myopia and high myopia were 16, 52 and 21 eyes in group A and 18, 55 and 24 eyes in group B(χ²=0.004, P>0.05). The patients with low amblyopia, medium amblyopia and severe amblyopia were 23, 49 and 17 eyes in group A and 26, 55 and 16 eyes in group B(χ²=0.136, P>0.05). All patients were followed up for 24 months to comparatively analyze the efficacy of two different combined therapies.

RESULTS: The recovery rate, effective rate and inefficacy rate was 35.96%, 40.45% and 23.60%, respectively in group A, and 56.70%, 26.80% and 16.49%, respectively in group B(χ²=6.022, P<0.05). The patients whose myopic degree developed ≤1.0D, 1.0D-3.0D and ≥3.0D were 3, 49 and 37 eyes in group A and 4, 69 and 24 eyes in group B after therapy(χ²=5.074, P<0.05).

CONCLUSION:The efficacy is better of minimal covering+ Haidinger brush + flicker red light + distance visual function training by red E standard logarithm visual acuity chart for treating children with myopic amblyopia and the develop of myopic degree were mild after therapy.