AIM: To compare the anesthetic effect of singleketmine and low-dose ketamine combined with proprofol in pediatric ocular trauma surgery.

METHODS: Sixty children with traumatic ocular disease were randomly divided into low-dose ketamine- propofol group(group A, n=30)and ketamine group(group B, n=30). The change of vital signs, effect and adverse reaction to anesthesia, intraocular pressure, the time of operation, duration of reviving and leaving operation room, ketamine mean consumption were all recorded in the preoperation, intraoperation and postoperation period.

RESULTS: There was no significant difference in thehemodynamic and respiratory function among 2 groups(P>0.05). The incidence of adverse reaction and hyper intraocular pressure was less than that of group B(P<0.05). Ketamine consumption in group B was significantly more than that in group A, recovery time were also longer in group B than those in group A(P<0.05).

CONCLUSION: The low-doseketamine combined with proprofol is a safe, efficacy anesthesia with stable hemodynamic function and intraocular pressure, quicker recovery and less adverse effect in pediatric ocular trauma surgery.