Intraocular lens as a drug delivery system has certain advantages in prevention of posterior capsular opacification, which include locally high drug concentrations, slight side effects and strong targeting. It can suppress the cells which have potential proliferation ability in situ, and avoid side effects and damages caused by direct medication to certain extent. The preparation of drugs modified intraocular lens which can reduce the incidence of posterior capsular opacification has become the study focus of many scholars. The article reviews the advances of this study at present.