半球后注射曲安奈德治疗甲状腺相关眼病
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Treatment of thyroid associated ophalmopathy by semiretrobulbar injection of triamcinolone acetonide
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    摘要:

    目的:评价半球后注射曲安奈德(triamcinolone acetonide,TA)治疗甲状腺相关眼病(thyroid associated ophthalmopathy,TAO)的临床效果。

    方法:对46例84眼甲状腺相关眼病患者以TA 40mg加20g/L利多卡因0.5mL行眼部半球后注射,每3wk 1次,连续4次为1疗程,1,3,6mo随访观察,记录眼部症状、体征情况。

    结果:患者43例自觉症状明显改善,眼球回退率83.6%,眼裂宽度缩小率85.2%,双眼视力改善率80.9%,眼球运动障碍、复视、斜视改善率80.5%。

    结论:半球后注射TA治疗甲状腺相关眼病效果明显,不良反应小,安全可靠。

    Abstract:

    AIM: To evaluate clinical effects of semiretrobulbar injection of triamcinolone acetonide(TA)for the treatment of thyroid associated ophalmopathy.

    METHODS: Totally 84 eyes of 46 cases with thyroid associated ophalmopathy were treated with semiretrobulbar injection of TA(40mg)with 20g/L Lidocaine(0.5 mL)for each eye once every three weeks for four times during one course of treatment. Then symptoms and signs of the patients were observed after 1 month, 3 months, 6 mouths.

    RESULTS: Symptoms of 43 cases were improved significantly. In all cases, eyeball recession rate was 83.6%, the palpebral fissure width reduction was 85.2%, visual acuity improvement was 80.9%, eye movement, strabismus, and diplopia improvement was 80.5%, compared to those before the treatment.

    CONCLUSION: The treatment of semiretrobulbar injection of TA for thyroid associated ophalmopathy is safe, effective and mild in side effect.

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王崇玉.半球后注射曲安奈德治疗甲状腺相关眼病.国际眼科杂志, 2013,13(2):398-399.

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  • 收稿日期:2012-09-06
  • 最后修改日期:2013-01-09
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