AIM: To investigate the diagnosis and treatment measures of the corneal herpetic endotheliitis.

METHODS: Forty cases of keratitis patients were selected, and according to the clinical symptoms and signs, parallel ordinary slit-lamp microscope examination and corneal laser scanning confocal microscope examinations, they were diagnosed with corneal herpetic endotheliitis, and randomly divided into two groups, 20 patients with simple anti-viral treatment as control group, 20 were treated with anti-viral combination glucocorticoid treatment as the observation group, the treatment effects were observed.

RESULTS: All patients successfully completed the treatment, the observation group did not appear expanded corneal ulcer, perforated ulcer complications during treatment. The total effective rate in observation group and control group was 70% and 50%, respectively, the difference between the two groups was statistically significant(P<0.05).

CONCLUSION: The herpes simplex viruskeratitis endothelial can easily be mixed up with a variety of eye diseases, it should be read in conjunction with the patient's history, clinical symptoms and laboratory diagnosed clinical antiviral therapy combined with corticosteroid therapy can be used to improve the therapeutic effect.