AIM: To evaluate the clinical curative effects of the compound anisodine's temple injection combined with the eye muscle massages in the treatment of the acquired ophthalmoplegia.

METHODS: According to the sequence of seeking medical advice, 52 cases(52 eyes)of the acquired ophthalmoplegia were randomly divided into the treatment group(eye muscle massage combined with the compound anisodine temple injection)27 cases 17 eyes and the matched control(normal regulations western medicine treat)25 cases 25 eyes. The treatment group was treated with eye muscle massage as well as temple injection of 2mL compound anisodine, once a day, 14 days a course—the treatment was injected 4 times on end and the medicine was stopped gradually. The treatment of the completely recovered was terminated at any time. Matched control: cortex hormone, vascular dilator drug and big dosage B clan vitamin were adopted in the treatment for 14-60 days.

RESULTS:The total efficient rate in treatment group was 85%, in control group was 52%. The difference was obvious. The curative effect of the treatment group surpassed the matched control, with statistical significance(χ²=6.71, P<0.01).

CONCLUSION: The method of the compound anisodine's temple injection combined with the eye muscle massages in the treatment of the acquired ophthalmoplegia not only shortens the treatment time but also posses easy procedure and safely. Meanwhile it is also an effectively clinical treatment method.