AIM: To probe into the clinical application value of vitrectomy with laser in treatment of proliferative diabetic retinopathy.

METHODS: Totally 89 patients(116 eyes)with proliferative diabetic retinopathy in our hospital were selected from March 2009 to March 2010. The patients were divided into control group(47 cases, 62 eyes)and study group(42 cases, 54 eyes)randomly. The patients in control group were treated with vitrectomy. The patients in study group were treated with vitrectomy combined with eye laser. The best-corrected visual acuity(BCVA)and FFA results of the patients before and after treatment, and occurrence of complications after treatment of the patients in two groups were compared and analyzed.

RESULTS: After treatment, the proportion of patients with best-corrected visual acuity <0.1 was reduced significantly in both groups(P<0.05), which were 40% and 28%, respectively. And the proportion of patients with a BCVA ranging from 0.5 to 1.0 was also improved significantly(P<0.05), which reached 24% and 41%, respectively. Compared with control group, the patients in study group after treatment, the rate of BCVA ranging from 0.5 to 1.0 was improved significantly, so did the rates of comprehensive regression of macular edema and partial regression of macular edema. While the rates of macular edema aggravation, retinal leakage and recurrence of vitreous bleeding were reduced significantly, the differences above were statistically significant(P<0.05).

CONCLUSION:Vitrectomy combined with laser treatment is an effective method for patients with proliferative diabetic retinopathy. It has a positive promoting role in improving postoperative visual acuity and reducing the occurrence of complications.