AIM: To observe the clinical effect of phacoemulsification and intraocular lens implantation combined with goniosynechialysis in the treatment of cataract and angle-closure glaucoma. To provide a reliable method for the treatment of cataract patients with angle-closure glaucoma.

METHODS: A retrospective analysis included clinical data of 95 patients(112 eyes)with cataract and angle-closure glaucoma which came from our hospital from Jan 2010 to Oct 2011. The patients were treated with phacoemulsification and intraocular lens implantation combined with goniosynechialysis. The clinical effect was compared between before and after treatment. The following clinical parameters were tested before and after treatment: visual acuity, intraocular pressure(IOP), anterior chamber depth, angle changes, and incidence of complications. Pair t test was used to analyze the measurement data.

RESULTS: The postoperative IOP of these patients was significantly lower than the preoperative at 1wk; 1, 6mo. There was significant difference between before and after treatment concerning visual acuity, anterior chamber depth, and angle changes(P<0.05). At different periods after treatment, all parameters of patients showed no significant differences. Comparison of the efficacy of before and after operation, chamber angle examination: all the subjects'(112 eyes)angle completely open after operation; the visual acuity, IOP, anterior chamber depth were 0.14±0.18, 34.5±6.5mmHg, 1.51±0.27mm respectively at pre-operation; after operation of 1wk; 1, 6mo, the visual acuity were 0.61±0.14, 0.61±0.2, 0.60±0.151 respectively; at 1wk; 1, 6mo of postoperation, the IOP were 13.1±3.7, 12.8±3.9, 12.9±4.3mmHg, and anterior chamber depth were 2.49±0.31, 2.45±0.39, 2.46±0.43mm. There were statistical differences at pre- and post-operation. Shallow anterior chamber, intraocular hypertension rate, and anterior chamber inflammation were treated efficiently and timely.

CONCLUSION: Phacoemulsification and intraocular lens implantation combined with goniosynechialysis in the treatment of cataract patients with angle-closure glaucoma can significantly improve visual acuity and reduce early complications of operation. It's safe, effective and convenient. The method of operation can be widely used.