AIM: To evaluate the safety and effectiveness of 23G micro-invasion vitrectomy combined surgery for proliferative diabetic retinopathy(PDR).

METHODS: Forty cases(40 eyes)with PDR of fibrovascular membrane range >5PD were randomly treated with 20G and 23G vitrectomy combined surgery. The medical records of patients were reviewed, and the visual acuity of postoperation, intraocular pressure, complications in preoperation or postoperation were analyzed.

RESULTS:After 1, 3 and 6mo of surgery, the best corrected visual acuity(BCVA)were LogMAR(0.88±0.43),(0.69±0.23),(0.45±0.17)in group 23G, and LogMAR(0.57±0.32),(0.41±0.21),(0.30±0.17)in group 20G. Compared with each other, the differences were not statistically significant. The patients were followed up 6-23mo after surgery.

CONCLUSION: 23G vitrectomy issafe and effective for complicated PDR.