AIM:To study and investigate the change situation of trace elements and body comprehensive immune state of patients with viral keratitis.

METHODS:Sixty-two patients with viral keratitis in our hospital from December 2011 to February 2014 were selected as observation group, 62 healthy persons with health education at the same time were the control group, then the serum and tear Zn, Cu, cellular immunity and erythrocyte immunity of two groups were compared, and the detection results of observation group with different types and severity degree were compared.

RESULTS:The serum and tear Zn of observation group was all lower than that in control group, serum and tear Cu was higher than that in control group, cellular immunity and erythrocyte immunity indexes were all worse than that in control group,the detection results of observation group with mild, moderate and severe infection had significant differences(P<0.05), while the detection results of observation group with herpes simplex keratitis and herpes zoster keratitis had no significant differences(P>0.05).

CONCLUSION: The change of trace elements and body comprehensive immune state of patients with viral keratitis are obvious,and the severity degree for the detection levels of keratitis are greater.