Abstract:AIM: To evaluate and observe the efficacy of silicon oil(SO), perfluoropropane(C3F8)and balanced salt solution(BSS)that can be used as tamponade during vitrectomy to treat proliferative diabetic retinopathy(PDR)complicated with vitreous hemorrhage(VH).
METHODS: Studied retrospectively on 74 eyes of 60 patients who underwent vitrectomy surgery with diabetic vitreous hemorrhage in our hospital during June 2008 and June 2014. Based on repeated prior examines on fundus details and the vitrectomy tamponades were chosen.All the patients had been followed up at least 3mo. Depending on different tamponades,the paitents were nonrandomized in three groups and contrasted as visual acuity,intraocular pressure(IOP)and complications respectively.
RESULTS: There was statistically significant difference among these three groups in preoperative eyesight(P<0.05). Moreover,the preoperative eyesight was statistically different between SO and BSS(P<0.05), and difference for the rest being not remarkable(P>0.05). The difference being statistically difference in the postoperative vision among these three groups(P<0.05). The further analysis showed that the paired-comparisons were statistically significant difference between SO and BSS(P<0.05), while the rest two groups of comparison were non-respectively(P>0.05). The preoperative visual function was in contrast to the postoperative(P<0.05). The IOP before surgery was not statistically significant difference(P>0.05). However,the difference among three groups being statistically in the postoperative vision(P<0.05), in addition,the difference existed in each group through pairwise comparison(P<0.05). The occurence rate of complications after surgery in this survey was 47%, the SO group was 50%, the C3F8 was 56%, the BSS group was 44%.
CONCLUSION: Vitrectomy is a safe and effective treatment that can help patients who have diabetic vitreous hemorrhage obtain better visual improvement. Because of the physicochemical properties and different conditions, there still has complications after surgery.
