AIM: To analyze the pathogenic bacteria and drug sensitivity in cases of canalicular inflammation.

METHODS: Lacrimal sac secretion from 57 cases(57 eyes)with canalicular inflammation. used to do bacterial cultures and drug sensitivity tests. Grind open the sulfur particles from canaliculus for bacterial smear.

RESULTS: After squeeze canalicular, there are 56 sulfur granules from 57 patients. All of the Sulfur particles smears were found in actinomycetes. A total of 55 from 57 cases of lacrimal secretions for bacterial culture were positive, and 63 strains were cultured. The main pathogen are Staphylococcus epidermidis, Streptococcus viridans and pneumococcus. Drug susceptibility test results showed that: rifampicin, cefoxitin, chloramphenicol, and mezlocillin are sensitivity.

CONCLUSION: Actinomycetes were the main pathogens to canalicular inflammation, and most of the presence of co-infection with other bacteria. Rifampin, cefoxitin, chloramphenicol, and mezlocillin are sensitivity canalicular inflammation.