AIM: To study the nerve fiber layer thickness and other parameters of optic disc in patients with retinitis pigmentosa.

METHODS: Totally 40 patients(80 eyes)with retinitis pigmentosa from April 2015 to April 2016 in our hospital were selected as the observation group and 40 healthy subjects as control group. All the subjects were examined by OCT. Disc parameters of retinal nerve fiber layer(RNFL)thickness, rim volume, cup volume, cup vertical diameter ratio, cup level diameter ratio, cup area ratio, rim area, cup area, disc area in temporal, superior, nasal and inferior quadrant were compared.

RESULTS: The thickness of the whole circle, nasal, temporal, superior and inferior RNFL in the eyes of RP group was significantly higher than those in the normal control group, the difference was statistically significant(P<0.05); RP eyes group with rim volume, cup volume, cup vertical diameter ratio, cup level diameter ratio, cup area ratio, rim area, cup area, disc area parameters were significantly higher than those in normal control group, the difference was statistically significant(P<0.05).

CONCLUSION: The mean thickness of RNFL in patients with retinitis pigmentosa at temporal, nasal, the whole circle compared with healthy subjects are thicker, while cup volume, cup vertical diameter ratio, cup level diameter ratio, cup area ratio, rim area and cup area increased.