AIM: To observe the early complications after Nd: YAG laser peripheral iridotomy(LPI)in patients with different anterior angle status and analysis the indications for laser treatment.

METHODS:This was a retrospective case series. Totally 362 cases(512 eyes)were involved in the treatment of Nd:YAG laser peripheral iridotomy in Xijing Hospital between January 2013 to June 2015. The early complications including iridemia, intraocular pressure spike, iridocyclitis, corneal or lens injury and others after laser peripheral iridotomy were analyzed and followed up for 3mo.

RESULTS:Totally 274 females(416 eyes)and 88 males(96 eyes)were involved in the study. Among the 512 eyes identified, 248 eyes had primary angle closure glaucoma(PACG), 108 eyes had primary angle closure(PAC), 72 eyes had primary angle closure suspect(PACS), 66 eyes had no signs or symptoms(the fellow eye of PACG), and 18 eyes had secondary glaucoma or ocular hypertension with pupillary block. After LPI, 107 eyes(20.9%)had iridemia, 85 eyes(16.6%)had intraocular pressure spike, 14 eyes(2.7%)had iridocyclitis, 10 eyes(2%)had corneal injury, 2 eyes(0.4%)had lens injury, 1 eye(0.2%)had decompression retinopathy, and 2 eyes(0.4%)had exudative retinal detachment. The incidence of iridemia was highest among patients with acute PACG(33.7%, P=0.019), and the incidence of intraocular pressure spike was highest among patients with chronic PACG(23.0%, P=0.047).

CONCLUSION: The most common complications of Nd:YAG LPI include iridemia and intraocular pressure spike. Whether PACG patients are more likely to have these complications needs further study. Rare serious complications like decompression retinopathy and exudative retinal detachment should be considered. The indications and timing of LPI should also be chosen carefully according to the patient's specific condition.