健康学龄儿童视觉诱发电位的研究
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Characteristics of healthy school-age children's visual evoke potentials
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    摘要:

    目的:本文将对健康学龄儿童的闪光视觉诱发电位(FVEP)及图形诱发电位(PVEP)的特征进行总结概况,研究性别、年龄以及其他生理因素对视觉诱发电位结果的影响,并将两种诱发电位从方法到结果进行比较。

    方法:选取101名健康儿童(5~14.4岁,平均8.27岁),分别进行FVEP及PVEP检查。应用SPSS 13.0软件对结果进行统计分析。

    结果:PVEP诱发出的图形简单并且稳定,FVEP诱发出的图形变化较大。PVEP中女性儿童P100潜伏期较男性儿童的短,但不具备显著性差异。在FVEP中没有显示出性别差异。在左右眼对比中我们发现左眼P100波幅要比右眼波幅高,在FVEP研究中没有显示出左右眼的差异。在年龄指标上,PVEP及FVEP各项参数都没有显示与年龄具有相关性。最后FVEP与PVEP两种方法进行相关性比照,我们发现两者的相关性小。

    结论:通过此次研究,我们发现性别、年龄等生理因素对儿童期视觉诱发电位影响不大。两种诱发电位的方法不具备内在联系,这与两者在大脑的应答区域不同相关。因此在视神经系统的检查上,两者应该互相补充。

    Abstract:

    AIM: To conclude the characteristics of flash visual evoke potentials(FVEP), and pattern visual evoke potentials(PVEP)of the healthy school-age children. And to compare the two methods, in order to find the association of them, and to find the impact of sex, age, and the other biological variables.

    METHODS: A total of 101 healthy children were recruited(age from 5 to 14.4y, mean 8.27y). Each of them was underwent FVEP and PVEP examinations. Then the results were statistically analyzed by SPSS 13.0.

    RESULTS: The curves of PVEP are simple and stable, while FVEP waveforms are variable. The latency of P100 of females is shorter than males. However there was no significant difference for FVEP in sex control. To compare the parameters between the two hemispheres, the amplitude of P100 of left eyes were higher than the right side. FVEP showed no difference in the two hemispheres either. There was no significant difference for age-dependent decreased in neither PVEP nor FVEP. And in a regression analysis of the FVEP and PVEP, we could not find the inner connection of the two methods.

    CONCLUSION: Based on our research, there were no significant differences in age level or sex control in the period of school-age children. And there is no inner connection of the two methods. The differences between the PVEP and FVEP results might be due to the origin of these two responses. And these two stimuli should be used in a complementary manner not as alternative examinations.

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宁书尧,杨思达.健康学龄儿童视觉诱发电位的研究.国际眼科杂志, 2017,17(7):1221-1225.

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  • 收稿日期:2016-06-23
  • 最后修改日期:2017-04-12
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  • 在线发布日期: 2017-06-26
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