AIM: To study the effect of residual triamcinolone acetonide(TA)to intraocular pressure(IOP)and retinal thickness in patients after vitrectomy.

METHODS: Retrospective study. The medical data of 83 patients(83 eyes)after vitrectomy in our hospital from October 2016 to October 2017 were analyzed retrospectively. The 83 patients were treated with TA as vitreous dyeing. Vitreous cavity was not filled with silicone oil or gas. Totally 32 eyes were observed that triamcinolone acetonide was residual in vitreous cavity, 51 eyes were not observed the residual, and after 1wk and 3mo, intraocular pressure and macular center concave thickness(CMT)of two groups was compared.

RESULTS: There was no statistical difference in preoperative average intraocular pressure between two groups(t=0.56, P>0.05). After 1wk, IOP of no residual group was 15.48±3.8mmhg, IOP of residual Group was 20.09±6.14mmhg. IOP of residual group were higher than IOP of no residual group, the difference was statistically significant(t=3.81,P<0.05). After 3mo, postoperative average IOP was 13.75±2.35mmhg, IOP of residual Group was 16.26±2.52mmhg, IOP of residual group was higher than IOP of no residual group, the difference was statistically significant(t=4.54, P<0.05). After 1wk, the average CMT of no residue group was 240.57±42.69μm, that of residual group was 215.03±18.38, and the difference was statistically significant(t=3.75,P<0.05). After 3mo, there was no statistical significance on the average CMT between no residual group and residual group(t=0.21, P>0.05).

CONCLUSION: The residual triamcinolone acetonide as a dyeing agent during vitrectomy may raise the risk of postoperative intraocular pressure in short term, and after 3mo without any significant effect on the thickness of macular center.