AIM:To compare the efficacy of transscleral cyclophotocoagulation(TSCP)with two different laser parameters.

METHODS: A total of 46 cases with refractory glaucoma(46 eyes)who underwent TSCP from January 2014 to December 2018 were analyzed retrospectively. According to the laser parameters, all cases were divided into low-power group(treated by low-power TSCP)and conventional parameter group(treated by conventional parameter TSCP). Intraocular pressures(IOP), best-corrected visual acuity(BCVA), number of anti-glaucoma drugs and complications were observed and compared between the two groups.

RESULTS: There was no significant difference of IOP between the two groups at postoperative 1d, 1wk, 1mo and 3mo(all P>0.05). The total success rate was 87% in the low-power group while 83% in the conventional parameter group(P=1.000).The overall incidence of complications of the low-power group(39%)was lower than that of the conventional parameter group(78%)(P=0.007)at postoperative 3mo. The early postoperative pain score of the low-power group was significantly lower than that of the conventional parameter group(P=0.007).

CONCLUSION:Compared with conventional parameters, TSCP with lower power may reduce IOP similarly with less pain and fewer complications.