Citation:Liu L,Liu LM,Hu YD,Hua R,Chen J,Zhou Y,Wan C,Huang LL,Wu JY,Geng J,Chen L.Hospital based epidemiological study for diabetic retinopathy: study design and preliminary results.Int J Ophthalmol 2011;4(5):543-545,doi:10.3980/j.issn.2222-3959.2011.05.16
Hospital based epidemiological study for diabetic retinopathy: study design and preliminary results
  
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DOI:10.3980/j.issn.2222-3959.2011.05.16
Key Words:diabetic retinopathy  prevalence  epidemiolo- gical study
Fund Project:Supported by Liaoning Medical Peak Construction Projects Foundation, China (No. 2010016)
                                
AuthorInstitution
Lei Liu Department of Ophthalmology, the First Affiliated Hospital, China Medical University, Shenyang , Liaoning Province, China
Li-Min Liu Department of Ophthalmology, the First Affiliated Hospital, China Medical University, Shenyang , Liaoning Province, China
Yue-Dong Hu Department of Ophthalmology, the First Affiliated Hospital, China Medical University, Shenyang , Liaoning Province, China
Rui Hua Department of Ophthalmology, the First Affiliated Hospital, China Medical University, Shenyang , Liaoning Province, China
Jun Chen Department of Ophthalmology, the First Affiliated Hospital, China Medical University, Shenyang , Liaoning Province, China
Yun Zhou Department of Ophthalmology, the First Affiliated Hospital, China Medical University, Shenyang , Liaoning Province, China
Chao Wan Department of Ophthalmology, the First Affiliated Hospital, China Medical University, Shenyang , Liaoning Province, China
Le-Le Huang Department of Ophthalmology, the First Affiliated Hospital, China Medical University, Shenyang , Liaoning Province, China
Jing-Yang Wu Department of Ophthalmology, the First Affiliated Hospital, China Medical University, Shenyang , Liaoning Province, China
Jin Geng Department of Ophthalmology, the First Affiliated Hospital, China Medical University, Shenyang , Liaoning Province, China
Lei Chen Department of Ophthalmology, the First Affiliated Hospital, China Medical University, Shenyang , Liaoning Province, China
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Abstract:
      AIM: To describe the design and preliminary results of the hospital based epidemiological study for diabetic retinopathy(HBESDR), an ongoing epidemiological study to estimate the prevalence of diabetic retinopathy(DR) and to elucidate the clinical, anthropometric, biochemical and any other risk factors associated with diabetic retinopathy.

    METHODS: Totally 2000 diabetes will be recruited from the Diabetes eye clinic in the First Affiliated Hospital of China Medical University. All subjects underwent blood sugar estimation and Oral Glucose Tolerance Test to diagnose diabetes. All diabetes would undergo complete questionnaire, a comprehensive eye examination. Blood and urine would be collected for biochemical investigations. All fundus photographs for any DR will be graded. Participants who need treatment will be sent to the ophthalmic clinic and follow-up interval program for all subjects will be suggested. A computerized database is created for the records.

    RESULTS: To date, 1174 diabetes have been recruited, there were 350(29.81%) DR in all diabetes, most of them were with mild non-proliferative diabetic retinopathy (NPDR) (139, 39.71%); 71(20.29%) moderate NPDR, 66(18.86%) severe NPDR, 74(21.14%) proliferative diabetic retinopathy (PDR). Females, longer duration of diabetes, family history of diabetes and hypertension had a statistically significant increase in risk of any DR.

    CONCLUSION: The study is expected to provide an estimate of the overall prevalence of DR and the prevalence with different duration of diabetes and also a better understanding of the risk factors associated with DR.

    

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