Citation:Pan HW,Iakymenko S,Xu JT,Hou GH,Sun BJ,Zheng AN.Implantation of Iakymenko keratoprosthesis in patients with severe ocular injury.Int J Ophthalmol 2012;5(2):167-171,doi:10.3980/j.issn.2222-3959.2012.02.10
Implantation of Iakymenko keratoprosthesis in patients with severe ocular injury
Received:December 19, 2011  Revised:March 20, 2012
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DOI:10.3980/j.issn.2222-3959.2012.02.10
Key Words:Iakymenko keratoprosthesis; visual rehabilitation; complications
Fund Project:Supported by National Natural Science Foundation of China (No. 81000368); Medical Scientific Research Foundation of Guangdong Province, China (B2008091, A2011327)
                 
AuthorInstitution
Hong-Wei Pan Department of Ophthalmology, the First Affiliated Hospital of Jinan University, Guangzhou , Guangdong Province, China; Institute of Ophthalmology, Medical College, Jinan University, Guangzhou , Guangdong Province, China; Key Laboratory for Regenerative Medicine, Ministry of Education, Jinan University, Guangzhou , Guangdong Province, China
Stanislav Iakymenko The Filatov Institute of Eye Disease and Tissue Therapy, Odessa, Ukraine
Jin-Tang Xu Department of Ophthalmology, the First Affiliated Hospital of Jinan University, Guangzhou , Guangdong Province, China; Institute of Ophthalmology, Medical College, Jinan University, Guangzhou , Guangdong Province, China
Guang-Hui Hou Department of Ophthalmology, the Third Affiliated Hospital of Jinan University, Zhuhai , Guangdong Province,China
Bing-Ji Sun Henan Eye Institute, Zhengzhou , Henan Province, China
A-Ning Zheng Institute of Ophthalmology, Medical College, Jinan University, Guangzhou , Guangdong Province, China
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Abstract:
      AIM: To present the results of implantation of Iakymenko keratoprosthesis in five patients with vascularized corneal leukoma caused by severe ocular injury.

    

    METHODS: Iakymenko keratoprosthesis was implanted into 5 eyes of 5 patients: 4 patients were suffered from chemical burns and 1 patient from explosive injury. The preoperative visual acuity ranged from light perception to hand motion. The implantation surgery was composed of two-stage procedures. The follow-up period was from 9 months to 11 years. The outcome measures were visual acuity, retention, and complications of the keratoprosthesis.

    RESULTS: Vision improvements were achieved in most patients. All keratoprosthesis were retained within the follow-up period. Corneal melting occurred in one patient and fibrous closure in another patient, both of which were successfully treated. Retinal detachment occurred in one patient after surgery.

    

    CONCLUSION: Iakymenko keratoprosthesis seems to be a promising alternative for the patients with severe corneal injury, but further investigation is needed to evaluate the role of Iakymenko keratoprosthesis.

PMC FullText Html:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359031/
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