| Citation:Wang XM,Cui DM,Zhen L,Yang X,Huo LJ,Liu X,Zeng JW.Characteristics of the macula in amblyopic eyes by optical coherence tomography.Int J Ophthalmol 2012;5(2):172-176,doi:10.3980/j.issn.2222-3959.2012.02.11 |
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| Characteristics of the macula in amblyopic eyes by optical coherence tomography |
| Received: November 24, 2011 Revised: March 29, 2012 |
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| DOI：10.3980/j.issn.2222-3959.2012.02.11 |
| Key Words:amblyopia macula flava optical coherence tomography |
| Fund Project:Supported by Key Projects in the Medicine Health Science and Technology from Guangzhou, China (No.201102A211005); Fundamental Research Funds of State Key Laboratory of Ophthalmology, China |
| Author | Institution | | Xin-Mei Wang | State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, SunYat-sen University, Guangzhou 510060, Guangdong Province, China
;Department of Ophthalmology, the Fourth Affiliated Hospital, Harbin Medical University, Harbin 150001, Heilongjiang Province, China | | Dong-Mei Cui | State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, SunYat-sen University, Guangzhou 510060, Guangdong Province, China | | Ling Zhen | Department of Ophthalmology, the Fourth Affiliated Hospital, Harbin Medical University, Harbin 150001, Heilongjiang Province, China | | Xiao Yang | State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, SunYat-sen University, Guangzhou 510060, Guangdong Province, China | | Li-Jun Huo | State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, SunYat-sen University, Guangzhou 510060, Guangdong Province, China | | Xing Liu | State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, SunYat-sen University, Guangzhou 510060, Guangdong Province, China | | Jun-Wen Zeng | State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, SunYat-sen University, Guangzhou 510060, Guangdong Province, China |
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| Abstract: |
| AIM: To test the hypothesis that amblyopic neuroretina may have an altered thickness when compared to the normal.
METHODS: Twenty-five amblyopic, young patients between the ages of 7 and 11 years old were studied. The interested neuroretina areas are defined into 10 sub-regions according to superior-inferior, nasal-temoral, and peri-para axis, which cross the fovela structure. The thicknesses of ten, defined macular regions were separately measured by optical coherence tomography (OCT) and analyzed by t-test.
RESULTS: The average thickness of neuroretina in the exact foveola of the amblyopic eyes is larger than that of normal eyes (P<0.05), but the other nine regions have no significant difference. Interestingly, in both the normal and amblyopic eyes, the temporal area looks thinner than other quadrants (P<0.05).
CONCLUSION: Thickness alteration may be associated with amblyopic disorders in young patients. Studying a larger volume of subjects of similar age is required to confirm this observation. |
| PMC FullText Html:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3359032/ |
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