Citation:?rnek K,Büyüktortop N,?rnek N,O?urel R,Erbah?eci ?E,Onaran Z.Effect of 1% brinzolamide and 0.5% timolol fixed combination on intraocular pressure after cataract surgery with phacoemulsification.Int J Ophthalmol 2013;6(6):851-854,doi:10.3980/j.issn.2222-3959.2013.06.19
Effect of 1% brinzolamide and 0.5% timolol fixed combination on intraocular pressure after cataract surgery with phacoemulsification
Received:January 04, 2013  Revised:August 01, 2013
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DOI:10.3980/j.issn.2222-3959.2013.06.19
Key Words:brinzolamide  timolol  cataract surgery
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Kemal ?rnek Department of Ophthalmology, School of Medicine, K?r?kkale University, K?r?kkale 71100, Turkey.
Nesrin Büyüktortop Department of Ophthalmology, School of Medicine, K?r?kkale University, K?r?kkale 71100, Turkey.
Nurgül ?rnek Department of Ophthalmology, School of Medicine, K?r?kkale University, K?r?kkale 71100, Turkey.
Reyhan O?urel Department of Ophthalmology, School of Medicine, K?r?kkale University, K?r?kkale 71100, Turkey.
?nci Elif Erbah?eci Department of Ophthalmology, School of Medicine, K?r?kkale University, K?r?kkale 71100, Turkey.
Zafer Onaran Department of Ophthalmology, School of Medicine, K?r?kkale University, K?r?kkale 71100, Turkey.
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Abstract:
      AIM: To evaluate the effect of brinzolamide-timolol fixed combination on intraocular pressure (IOP) after cataract surgery.

    METHODS:The study included 92 eyes of 87 patients who underwent cataract surgery and intraocular lens implantation. Patients scheduled for phacoemulsification were assigned to 1 of 2 groups. The treatment group received 1 drop of brinzolamide-timolol fixed combination immediately after surgery, and the control group received no treatment. The IOP was measured preoperatively and at 2h and 24h postoperatively.

    RESULTS: The mean IOP change was lower in the treatment group than in the control group at 2h postoperatively. The difference between the mean IOP values of the two groups at 2h postoperatively was found to be statistically significant. Twenty-four hours after the surgery, the mean IOP change was still higher in the control group when compared to the treatment group.

    CONCLUSION: The fixed combination brinzolamide-timolol can effectively reduce IOP after cataract surgery.

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