Citation:Wang DY,Liu ML,Chen YL,Zhang XY,Xu YT,Wang JC,To CH,Wang JG,Liu Q.Short term effects of small incision lenticule extraction surgery on corneal endothelium.Int J Ophthalmol 2016;9(4):536-539,doi:10.18240/ijo.2016.04.09
Short term effects of small incision lenticule extraction surgery on corneal endothelium
Received:January 30, 2015  Revised:September 06, 2015
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DOI:10.18240/ijo.2016.04.09
Key Words:myopia  corneal endothelium  refractive surgery
Fund Project:Supported by the National Natural Science Foundation of China (No. 81261130021); Henry G Leong Endowed Professorship fund; PolyU research grant GUA32 for supporting the analysis work in Hong Kong.
                          
AuthorInstitution
Dan-Yang Wang State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou , Guangdong Province, China; Hainan Eye Hospital, Zhongshan Ophthamic Center, Sun Yat-sen University, Haikou , Hainan Province, China
Man-Li Liu State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou , Guangdong Province, China
Yi-Le Chen State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou , Guangdong Province, China
Xiao-Ying Zhang State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou , Guangdong Province, China
Yang-Tao Xu Department of Ophthalmology, Liu Zhou Worker’s Hospital, Liuzhou , Guangxi Zhuang Autonomous Region, China
Jian-Chao Wang Department of Ophthalmology, the Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an , Shaanxi Province, China
Chi-Ho To State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou , Guangdong Province, China; Laboratory of Experimental Optometry, Centre for Myopia Research, School of Optometry, the Hong Kong Polytechnic University, Hong Kong, China
Jian-Guo Wang Wuzhishan Ophthalmic Hospital, Wuzhishan , Hainan Province, China
Quan Liu State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou , Guangdong Province, China; Laboratory of Experimental Optometry, Centre for Myopia Research, School of Optometry, the Hong Kong Polytechnic University, Hong Kong, China
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Abstract:
      AIM: To assess the effects of small incision lenticule extraction (SMILE) surgery on the corneal endothelium at 1d to 1mo postoperatively.

    METHODS: A retrospective, observational study was conducted on 47 patients (47 eyes) who received SMILE surgery. Patients were grouped according to contact lens wear condition. The corneal endothelium was examined preoperatively and at 1d, 1wk and 1mo postoperatively. The corneal endothelium was analyzed for endothelial cell density (ECD), percentage of hexagonal cells, and coefficient of variation (CV) of cell size.

    RESULTS: There were no significant decrease in the ECD, percentage of hexagonal cells or increase in CV at 1d, 1wk and 1mo postoperatively (P>0.05). However, there was a small increase of ECD by 2.88% in contact lens wearers (78.26±113.62 cell/mm2, P<0.05).

    CONCLUSION: SMILE has no significant adverse effects on the corneal ECD and morphology during 1mo follow-up time.

PMC FullText Html:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4853347/
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