Citation:Zhao PF,Li SM,Lu J,Song HM,Zhang J,Zhou YH,Wang NL.Effects of higher-order aberrations on contrast sensitivity in normal eyes of a large myopic population.Int J Ophthalmol 2017;10(9):1407-1411,doi:10.18240/ijo.2017.09.13
Effects of higher-order aberrations on contrast sensitivity in normal eyes of a large myopic population
Received:January 03, 2016  Revised:April 17, 2017
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DOI:10.18240/ijo.2017.09.13
Key Words:myopia  contrast sensitivity  higher-order aberrations  coma  spherical aberration
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AuthorInstitution
Peng-Fei Zhao Ophthalmic Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Lab, Beijing , China
Shi-Ming Li Ophthalmic Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Lab, Beijing , China
Jing Lu Department of Ophthalmology, Affiliated Hospital of Hebei Medical University, Baoding , Hebei Province, China
Hong-Min Song College of Applied Arts and Science, Beijing Union University, Beijing , China
Jing Zhang Ophthalmic Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Lab, Beijing , China
Yue-Hua Zhou Ophthalmic Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Lab, Beijing , China
Ning-Li Wang Ophthalmic Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Sciences Key Lab, Beijing , China
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Abstract:
      AIM: To study the relation between higher-order aberrations (HOAs) and contrast sensitivity (CS) in normal eyes among a population of laser in situ keratomileusis (LASIK) candidates.

    METHODS: In 6629 eyes of 3315 LASIK candidates, CS were measured under dark environment at the spatial frequencies of 1.5, 3, 6, 12 and 18 cycles per degree (c/d), respectively, using an Optec 6500 visual function tester. Meanwhile, ocular HOAs were measured for a 6.0 mm pupil with a Hartmann-Shack wavefront analyzer.

    RESULTS: In the study, the subjects with an average spherical equivalent of -4.86±2.07 D were included. HOAs decreased from the third to the sixth order aberrations with predominant aberrations of third-order coma, trefoil and fourth-order spherical aberration. At low and moderate spatial frequencies, CS was negatively correlated with the third-order coma and trefoil aberrations, and decreased with increasing Z31, but increased with increasing Z3-3 and Z5-1. At high spatial frequencies, CS decreased with increasing Z3-3 and increased with increasing Z5-1.

    CONCLUSION: At a large pupil size of 6.0 mm, the third-order aberrations, but not the total aberrations, are the main factors affecting CS. Vertical coma is negatively correlated with CS.

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