Citation:Sabetti L,Masedu F,Tresca C,Bianchi F,Valenti M.The use of choline in association with the Bangerter filters for the treatment of amblyopia.Int J Ophthalmol 2017;10(11):1777-1778,doi:10.18240/ijo.2017.11.22
The use of choline in association with the Bangerter filters for the treatment of amblyopia
Received:February 04, 2017  Revised:May 22, 2017
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DOI:10.18240/ijo.2017.11.22
Key Words:choline  amblyopia  Bangerter filter  visual acuity  ocular motility
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Lelio Sabetti Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila 67100, Italy
Francesco Masedu Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila 67100, Italy
Chiara Tresca Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila 67100, Italy
Federica Bianchi Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila 67100, Italy
Marco Valenti Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila 67100, Italy
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Abstract:
      The study investigated the effects of choline combined with Bangerter filter in the treatment of amblyopia. All amblyopic subjects used a Bangerter filter on the corrective spectacle lens (1d over the left eye, 1d over the right eye). Choline was then administered orally to 39 patients once daily, five days per week for the entire study period. Subjects treated with the Bangerter filter showed a mean visual acuity of 0.27 logMAR; at 12mo of treatment, the mean visual acuity reached 0.09 logMAR. Patients treated with the Bangerter filter and citicoline showed a mean visual acuity of 0.35 logMAR; at 12mo of treatment, the mean visual acuity reached 0.01 logMAR. No significant changes in the angle of deviation were observed in both groups. Subjects in both forms of amblyopia therapies demonstrated an increase in visual acuity. However, these effects were markedly enhanced when coupled with the administration of choline. Findings suggest that the effects are particularly relevant in the more severe amblyopic cases.
PMC FullText Html:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5686380/
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