Citation:Fu D,Wang L,Zhou XT,Yu ZQ.Cap morphology after small-incision lenticule extraction and its effects on intraocular scattering.Int J Ophthalmol 2018;11(3):456-461,doi:10.18240/ijo.2018.03.16
Cap morphology after small-incision lenticule extraction and its effects on intraocular scattering
Received:May 26, 2017  Revised:October 14, 2017
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DOI:10.18240/ijo.2018.03.16
Key Words:corneal cap  intraocular scattering  microdistortion  small-incision lenticule extraction
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Dan Fu Eye and ENT Hospital of Fudan University, Shanghai , China
Lin Wang Eye and ENT Hospital of Fudan University, Shanghai , China
Xing-Tao Zhou Eye and ENT Hospital of Fudan University, Shanghai , China; Myopia Key Laboratory of the Health Ministry, Shanghai , China
Zhi-Qiang Yu Eye and ENT Hospital of Fudan University, Shanghai , China; Myopia Key Laboratory of the Health Ministry, Shanghai , China
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Abstract:
      AIM: To investigate cap morphology after small-incision lenticule extraction (SMILE) and its effects on intraocular scattering.

    METHODS: Sixty-five eyes of 33 patients undergoing SMILE were enrolled. In addition to regular evaluation, Fourier-domain optical coherence tomography was used to investigate cap thickness at 1d, 1wk, 1 and 3mo postoperatively. The optical quality including modulation transfer function cutoff frequency, Strehl ratio, Optical Quality Analysis System (OQAS) values, and objective scattering index (OSI), were evaluated using OQASTM.

    RESULTS: Cap thickness decreased from 1d to 1wk (P<0.001), but remained higher than intended thickness of 120 μm after 3mo (P<0.001). Cap thickness in central area was thinner than that of in the paracentral and peripheral areas (P<0.0001). Total number of microdistortions decreased from 1d to 3mo (P<0.0001). Pearson analysis revealed a weak correlation between OSI and standard deviation of cap thickness at 1d and 1mo, as well as between range of cap thickness and OSI at 1mo. No correlation was found between microdistortion and OSI, but a negative correlation existed between microdistortion and range at 1d and 1moafter surgery.

    CONCLUSION: The corneal cap tends to be more accurate and regular with time lapse. Better cap morphology tends to contribute less intraocular scattering in the eyes undergoing SMILE.

PMC FullText Html:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5861236/
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