Citation:Xie HT,Li J,Liu Y,Jiang DL,Shen RF,Zhang MC.Cryopreserved limbal lamellar keratoplasty for peripheral corneal and limbal reconstruction.Int J Ophthalmol 2018;11(4):699-702,doi:10.18240/ijo.2018.04.27
Cryopreserved limbal lamellar keratoplasty for peripheral corneal and limbal reconstruction
Received:May 15, 2017  Revised:August 28, 2017
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DOI:10.18240/ijo.2018.04.27
Key Words:cryopreserve; epithelialization; lamellar keratoplasty; limbus; neovascularization; ocular surface; peripheral corneal and limbal diseases; stem cells
Fund Project:Supported by National Natural Science Foundation of China (No.81300736; No.81370993).
                 
AuthorInstitution
Hua-Tao Xie Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China
Jing Li Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China
Yang Liu Schepens Eye Research Institute, Massachusetts Eye and Ear, Harvard Medical School, Boston 02114, USA
Dong-Ling Jiang Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China
Rui-Fen Shen Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China
Ming-Chang Zhang Department of Ophthalmology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan , China
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Abstract:
      This study aimed to evaluate the outcomes and described the recovery process of cryopreserved limbal lamellar keratoplasty (CLLK) for peripheral corneal and limbal diseases. Thirteen eyes of 12 patients with a mean age of 41±23.9y were included. The average follow-up was 12.1±5.6mo. Stable ocular surface was achieved in all eyes at last follow-up. Epithelialization originated from both recipient and graft in 9 eyes. We conclude that CLLK compensates for the shortage of donor corneas and cryopreserved limbal grafts provide epithelialization sources in ocular surface reconstruction.
PMC FullText Html:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902380/
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