Citation:Reddy JK,Chaitanya V,Shah N,Guduru VP,Khan S,Kuttupalayam S.Safety & efficacy of single subconjunctival triamcinolone 5 mg depot vs topical loteprednol post cataract surgery: less drop cataract surgery.Int J Ophthalmol 2019;12(5):774-778,doi:10.18240/ijo.2019.05.11
Safety & efficacy of single subconjunctival triamcinolone 5 mg depot vs topical loteprednol post cataract surgery: less drop cataract surgery
Received:July 13, 2018  Revised:February 25, 2019
Email this Article  Add to Favorites  Print
DOI:10.18240/ijo.2019.05.11
Key Words:intraocular pressure  subconjunctival triamcinolone acetonide  phacoemulsification  loteprednol  cells/flare  less drop cataract surgery
Fund Project:
                 
AuthorInstitution
Jagadeesh Kumar Reddy Department of Cornea, Sankara Eye Hospital, Coimbatore , Tamil Nadu, India
Vivek Chaitanya Department of Cornea, Sankara Eye Hospital, Coimbatore , Tamil Nadu, India
Neeraj Shah Department of Cornea, Sankara Eye Hospital, Coimbatore , Tamil Nadu, India
Venkata Prabhakar Guduru Department of Cornea, Sankara Eye Hospital, Coimbatore , Tamil Nadu, India
Shadab Khan Department of Cornea, Sankara Eye Hospital, Coimbatore , Tamil Nadu, India
Siddharthan Kuttupalayam Department of Cornea, Sankara Eye Hospital, Coimbatore , Tamil Nadu, India
Hits: 1138
Download times: 204
Abstract:
      AIM: To do a randomized prospective interventional study for comparing the effects of a single subconjunctival triamcinolone acetonide (SCTA) injection to tapering topical loteprednol in patients undergoing phacoemulsification surgery under topical anesthesia.

    METHODS: A total of 400 patients were randomized into 2 groups; Group A (200 patients) received 5 mg SCTA at the end of surgery and topical ketorolac tromethamine (0.5%) with ofloxacin (0.3%) combination for 3wk. Group B (200 patients) received tapering topical loteprednol etabonate (0.5%) along with ofloxacin (0.3%) and ketorolac tromethamine (0.5%) for 3wk. Outcomes evaluated were intraocular pressure (IOP), anterior chamber cells/flare and macular oedema postoperatively at 1, 6 and 12wk.

    RESULTS: Baseline parameters were almost similar in both the groups. No statistical difference was seen between the preoperative and postoperative IOP values for Group A (P=0.82) and Group B (P=0.61) and postoperative IOP values in between both groups (P=0.14) at 1wk. Incidence of cells/flare postoperative was statistically not significant (P=0.82) in both groups at all follow up visits. Postoperative macular oedema was not observed at any follow up visit.

    CONCLUSION: SCTA appears to be an effective alternative to prolong postoperative topical steroid use.

Supplementary Material
PDF Fulltext  Download reader  View/Add Comment