| Citation:Garrido-Hermosilla AM,Méndez-Muros M,Gutiérrez-Sánchez E,Morales-Portillo C,Díaz-Granda MJ,Esteban-González E,Relimpio-López I,Martínez-Brocca MA,Rodríguez-de-la-Rúa-Franch E.Renal function and choroidal thickness using swept-source optical coherence tomography in diabetic patients.Int J Ophthalmol 2019;12(6):985-989,doi:10.18240/ijo.2019.06.17 |
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| Renal function and choroidal thickness using swept-source optical coherence tomography in diabetic patients |
| Received:October 09, 2018 Revised:November 26, 2018 |
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| DOI：10.18240/ijo.2019.06.17 |
| Key Words:choroidal thickness renal function swept-source optical coherence tomography spectral-domain optical coherence tomography diabetes mellitus |
| Fund Project:OFTARED “RD16/0008/0010”, funded by Instituto de Salud Carlos III, integrated in the national I+D+i 2013-2016 and co-funded by European Union (ERDF/ESF, “Investing in your future”) |
| Author | Institution |
| Antonio Manuel Garrido-Hermosilla |
Department of Ophthalmology, Virgen Macarena University Hospital, Seville 41009, Spain; OftaRed, Institute of Health Carlos III, Madrid, Spain |
| Mariola Méndez-Muros |
Department of Endocrinology and Nutrition, Virgen Macarena University Hospital, Seville 41009, Spain |
| Estanislao Gutiérrez-Sánchez |
Department of Ophthalmology, Virgen Macarena University Hospital, Seville 41009, Spain; OftaRed, Institute of Health Carlos III, Madrid, Spain |
| Cristóbal Morales-Portillo |
Department of Endocrinology and Nutrition, Virgen Macarena University Hospital, Seville 41009, Spain |
| María Jesús Díaz-Granda |
Department of Ophthalmology, Virgen Macarena University Hospital, Seville 41009, Spain; OftaRed, Institute of Health Carlos III, Madrid, Spain |
| Eduardo Esteban-González |
Department of Ophthalmology, Virgen Macarena University Hospital, Seville 41009, Spain; OftaRed, Institute of Health Carlos III, Madrid, Spain |
| Isabel Relimpio-López |
Department of Ophthalmology, Virgen Macarena University Hospital, Seville 41009, Spain; OftaRed, Institute of Health Carlos III, Madrid, Spain |
| María Asunción Martínez-Brocca |
Department of Endocrinology and Nutrition, Virgen Macarena University Hospital, Seville 41009, Spain |
| Enrique Rodríguez-de-la-Rúa-Franch |
Department of Ophthalmology, Virgen Macarena University Hospital, Seville 41009, Spain; OftaRed, Institute of Health Carlos III, Madrid, Spain |
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| Abstract: |
| AIM: To assess the relationship between choroidal thickness and renal function in diabetic patients.
METHODS: Cross-sectional retrospective clinical study of 42 eyes of 21 ocular treatment-naïve diabetic patients. Demographic data included: age, sex, type and course of diabetes. Ocular data included: severity of diabetic retinopathy; retinal thickness at the central macular region, as well as choroidal thickness at the central and paracentral quadrants, using automatically generated maps by swept-source optical coherence tomography; presence of cystic macular edema; and ocular axial length (AXL). Lab-test parameters included: glycated hemoglobin (HbA1c), albuminuria, albumin/creatinine ratio in urine, and glomerular filtration rate.
RESULTS: A significant negative correlation was mainly observed between several choroidal thicknesses, age (P<0.020) and ocular AXL (P<0.030). On the contrary, a significant positive correlation was found between all choroidal thicknesses, HbA1c (P<0.035) and albuminuria (P<0.040).
CONCLUSION: Choroidal thickness can represent an additional tool to help clinicians predicting the renal status in ocular treatment-naïve diabetic patients. |
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