Citation:Ju RH,Chen Y,Chen HS,Zhou WJ,Yang W,Lin ZD,Wu ZM.Changes in ocular surface status and dry eye symptoms following femtosecond laser-assisted cataract surgery.Int J Ophthalmol 2019;12(7):1122-1126,doi:10.18240/ijo.2019.07.11
Changes in ocular surface status and dry eye symptoms following femtosecond laser-assisted cataract surgery
Received:January 29, 2019  Revised:April 28, 2019
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DOI:10.18240/ijo.2019.07.11
Key Words:ocular surface  dry eye  tear film  femtosecond laser-assisted cataract surgery
Fund Project:Supported by Medical Science and Technology Research Foundation Project of Guangdong Province (No.C2017029); Science and Technology Project of Yuexiu District, Guangzhou (No.2017-WS-013).
                    
AuthorInstitution
Rui-Hong Ju Guangzhou Aier Eye Hospital, Guangzhou , Guangdong Province, China
Yun Chen Guangzhou Aier Eye Hospital, Guangzhou , Guangdong Province, China
Hai-Song Chen Guangzhou Aier Eye Hospital, Guangzhou , Guangdong Province, China
Wei-Jian Zhou Guangzhou Aier Eye Hospital, Guangzhou , Guangdong Province, China
Wei Yang Guangzhou Aier Eye Hospital, Guangzhou , Guangdong Province, China
Zhen-De Lin Guangzhou Aier Eye Hospital, Guangzhou , Guangdong Province, China
Zhe-Ming Wu Guangzhou Aier Eye Hospital, Guangzhou , Guangdong Province, China
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Abstract:
      AIM: To observe the changes in ocular surface and the dry eye symptoms following femtosecond laser-assisted cataract surgery (FLACS).

    METHODS: Patients with no eye signs or symptoms in Guangzhou Aier Eye Hospital between October 2017 and September 2018, who underwent FLACS and intraocular lens (IOL) implantation for age-related cataract were enrolled. Tear film stability assessed with OCULUS Keratograph 5M, Schirmer’s I test (SIT), and corneal fluorescein staining (CFS) were evaluated before and after surgery at 1d, 1wk, 1, and 3mo in order. Ocular Surface Disease Index scores (OSDI) and Subjective Symptom Questionnaires (SSQs) were recorded at the same time point.

    RESULTS: Thirty-eight eyes of 38 patients were enrolled. The noninvasive tear film break-up time (first break-up time and average break-up time) decreased in a peak at the 1wk visit, and then increased to basic levels at 1mo. The tear meniscus height (TMH) increased transiently at 1d, and declined in the following 3mo visits. The SIT had a transient increase at 1d (P=0.357) and a decrease at 1wk and 1mo (both P<0.05) but returned to the preoperative levels at 3mo after surgery (P=0.062). CFS scores were significantly improved compared with those before surgery, and had a statistical difference (P<0.05). OSDI scores and SSQs after surgery were obviously higher, and had a statistical difference (P<0.001) but didn’t return to the basic level by 3mo.

    CONCLUSION: Dry eye signs and symptoms can occur immediately following FLACS and have a peak severity on day 7 postoperatively. Most signs of dry eye can return to preoperative basic levels within 3mo postoperatively. However, all cases can not recover from CFS and dry eye symptoms at 3mo postoperatively.

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