Citation:Tan SY,Liu SW,Jiang SB.HIV/AIDS and ocular complications.Int J Ophthalmol 2009;2(2):95-105,doi:
HIV/AIDS and ocular complications
Received:February 10, 2009  Revised:February 13, 2009
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Key Words:HIV/AIDS  ocular complication  retinopathy  neoplasm  opportunistic infection  HAART
Fund Project:Supported by Natural Science Foundation of China (No. 30672496, U0832001 and 30729001); Culture Grant for Key Projects by Ministry of Education of China (No.706047)
        
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Sui-Yi Tan School of Pharmaceutical Sciences, Southern Medical University, Guangzhou , Guangdong Province, China ; Viral Immunology Laboratory, Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10065, USA
Shu-Wen Liu School of Pharmaceutical Sciences, Southern Medical University, Guangzhou , Guangdong Province, China
Shi-Bo Jiang 1 School of Pharmaceutical Sciences, Southern Medical University, Guangzhou , Guangdong Province, China 2 Viral Immunology Laboratory, Lindsley F. Kimball Research Institute, New York Blood Center, New York, NY 10065, USA
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Abstract:
      The introduction of highly active antiretroviral therapy (HAART) has greatly changed the pattern and natural history of ocular diseases of HIV-infected patients, resulting from the immune recovery and reduction of opportunistic infections. However, ophthalmic complication continues to be concern in AIDS even in the HAART era, especially in developing areas, where absolute majority of HIV-positive patients live. Lack of test facilities and experience, poor conditions of hygiene, different microbiological environment, absence of effective treatment etc., characterize the ophthalmic manifestation of HIV-infected patients in developing countries from that in developed regions and thus pose a great challenge to the ophthalmic treatment in developing area. Not only varied from region to region, ocular complications are distinctive between adults and children. At the same time, the side effects due to the application of HAART pose their own risks of ocular comp- lication and should, therefore, be given more resear
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