Highlighted Articles in Int J Ophthalmol Vol.11 No.4 2018
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Highlighted Articles in International Journal of Ophthalmology Vol.11 No.4, 2018

Basic Research

 

Effect of senescence marker protein 30 on the proliferation and apoptosis of human lens epithelial cells SRA01/04

衰老标记蛋白-30对人晶状体上皮细胞SRA01/04增殖和凋亡的影响

Xi Chen, Song-Man Li, Yan-Wei Li, Zi-Hao Han, Hao Liang
2018,11(4):553-558  DOI
10.18240/ijo.2018.04.03

The study aimed to study the effect of senescence marker protein 30 (SMP30) on the proliferation and apoptosis of human lens epithelial cell (HLEC) SRA01/04. Compared with previous studies, this study used lentivirus transfection technique to construct stable strains and visualized the effect of SMP30 content on HLEC from the cell level. It is meaning for using SMP30 anti-aging characteristic to change intraocular apoptosis and prevent cataract through eye drops in the future.

该文旨在研究衰老标记蛋白-30对人晶状体上皮细胞SRA01/04增殖和凋亡的影响。与以往的研究相比,此研究采用慢病毒转染技术构建稳定的菌株,直接从细胞水平观察携带衰老标记蛋白-30的人晶状体上皮细胞的改变。这一结果对于应用衰老标记蛋白-30的抗老化特性抑制眼内细胞凋亡并在将来通过滴眼液预防白内障的发生有指导意义。

 

http://www.ijo.cn/en_publish/2018/4/20180403.pdf  



Clinical Research

 

Photorefractive keratectomy after cataract surgery in uncommon cases: long-term results

罕见病例白内障手术后屈光性角膜切削术的远期疗效

Anna Maria Roszkowska, Mario Urso, Giuseppe Alberto Signorino, Leopoldo Spadea, Pasquale Aragona
2018,11(4):612-615   DOI
10.18240/ijo.2018.04.12

This paper evaluates the efficacy and safety of the excimer laser correction of the residual refractive errors after cataract extraction with IOL implantation in uncommon cases. It can be concluded that photorefractive keratectomy can be considered as a safe and effective procedure for correction of post cataract residual refractive errors providing the patients with their attempted visual acuity. Moreover, it results stable in the long term, yielding more effective and predictable outcome than intraocular surgery.

该文研究了白内障摘除联合人工晶状体植入后的罕见病例行准分子激光矫正残留屈光度的疗效和安全性。研究结果显示屈光性角膜切削术可作为改善白内障术后残留屈光不正并获得患者预期视力的安全可靠的方法。除此之外,其疗效长期稳定,比内眼手术更有效和可预测。


http://www.ijo.cn/en_publish/2018/4/20180412.pdf

 

Long-term outcomes of uveitic glaucoma treated with Ahmed valve implant in a series of Chinese patients

Ahmed青光眼引流阀植入治疗葡萄膜炎继发性青光眼中国患者的远期疗效

Ning Bao, Zheng-Xuan Jiang, Paul Coh, Li-Ming Tao

2018,11(4):629-634   DOI10.18240/ijo.2018.04.15

The authors reported five years’ outcome of patients with uveitic glaucoma who were treated with Ahmed glaucoma valve implantation. The main outcome of intraocular pressure, glaucoma medications, surgical complications, final best-corrected vision acuity, visual field and retinal nerve fiber layer were measured. The results showed that Ahmed glaucoma valve implantation is effective and safe for patients with uveitic glaucoma.

该文报道了关于Ahmed青光眼引流阀植入治疗葡萄膜炎继发性青光眼患者的五年远期疗效。其中,对主要观察指标眼压,青光眼药物,手术并发症,最佳矫正视力,视野和视网膜神经纤维层进行了评测。结果显示Ahmed青光眼引流阀植入治疗葡萄膜炎继发性青光眼患者是安全有效的。
http://www.ijo.cn/en_publish/2018/4/20180415.pdf

 

 

Comparison of optical quality after implantable collamer lens implantation and wavefront-guided laser in-situ keratomileusis

后房型人工晶状体植入术与波前像差引导LASIK术后视觉质量比较研究

Hong-Ting Liu, Zhou Zhou, Wu-Qiang Luo, Wen-Jing He, Owhofasa Agbedia, Jiang-Xia Wang, Jian-Zhong Huang, Xin Gao, Min Kong, Min Li, Li Li
2018,11(4):656-661     DOI10.18240/ijo.2018.04.20

This study accessed the objective scattering index (OSI), the values of modulation transfer function (MTF) cutoff frequency, Strehl ratio, and the Optical Quality Analysis System (OQAS) values (OVs) before surgery and three months after implantable collamer lens implantation and wavefront-guided laser in-situ keratomileusis. The result showed significant improvements in visual acuities postoperatively, with a significant reduction in spherical equivalent in both ICL and WG-LASIK group. ICL implantation has a less disturbance to optical quality than WG-LASIK. The OQAS system is a valuable complementary measurement to the wavefront aberrometers in evaluating the optical quality.

该研究提取了后房型人工晶状体植入术与波前像差引导LASIK术前以及术后三月客观散射指数(OSI)MTF截止频率、斯特尔比率、双通道视觉质量分析(OQAS)。结果显示,后房型人工晶状体植入组与波前像差引导LASIK术组术后视力均有明显改善,等效球镜显著降低。后房型人工晶体植入术相比波前像差引导LASIK术对视觉质量影响较小。OQAS对波前像差仪在评估光学质量方面是一种有效的补充测量方法。

http://www.ijo.cn/en_publish/2018/4/20180420.pdf



Investigation

 

Comparison of choroidal vessel thickness in children and adult eyes by enhanced-depth imaging optical coherence tomography imaging

通过频域相干光断层深度增强成像比较儿童和成年的脉络膜血管厚度

Daren Hanumunthadu, Jorge Ruiz-Medrano, Sunila Dumpala, Ayesha Jabeen, Asiya Jabeen, Abhilash Goud, José M Ruiz-Moreno, Jay Chhablani

2018,11(4):681-686   DOI10.18240/ijo.2018.04.24

The author report that choroidal thickness in adult eyes is significantly more than children eyes and this is associated with a corresponding decrease in large choroidal vessel thickness and an increase in medium choroidal vessel thickness at the subfoveal location. They hope that these analyses of choroidal layer alterations in ageing could be useful in aging changes within the choroid and chorioretinal disease in children.

作者通过研究得出,成年人的脉络膜厚度明显大于儿童,是由于位于黄斑中心凹下的脉络膜大血管层相应减少和脉络膜中血管层增加。作者希望这些脉络膜与年龄相关性研究对儿童年龄相关性脉络膜疾病与脉络膜视网膜病研究有所帮助。

http://www.ijo.cn/en_publish/2018/4/20180424.pdf

For more excellent articles in this issue please visit
http://www.ijo.cn/gjyken/ch/reader/issue_list.aspx?year_id=2018&quarter_id=4

 

 

 

 

 

Published date:2018-04-10Click:

Editors-in-Chief: Yan-Nian Hui and Peter Wiedemann

Established in April, 2008

ISSN 2222-3959 print

ISSN 2227-4898 online

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